发明名称 PYRROLIDINE DERIVATIVE
摘要 PROBLEM TO BE SOLVED: To provide a compound having DPP4(dipeptidyl peptidase IV)-inhibitory activity. SOLUTION: The compound is represented by formula(I)( wherein, all of the signs mean the same as defined in the Specification ). This compound, salts thereof, its solvate, its N-oxide form or their prodrugs have DPP4 inhibitory activities, respectively. Therefore, this compound is useful as a curative and/or prophylactic agent for diabetes(e.g. Type II diabetes), obesity and the like, or as a prophylactic and/or ameliorating agent for postprandial hyperglycemia, glucose tolerance abnormalities and the like. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007031396(A) 申请公布日期 2007.02.08
申请号 JP20050220074 申请日期 2005.07.29
申请人 ONO PHARMACEUT CO LTD 发明人 KONMON TAKAHIRO;HATAKEYAMA AKIRA;KONDO TAKASHI;SAYAMA YUKINORI
分类号 C07D207/16;A61K31/40;A61K31/4025;A61K31/4035;A61K31/427;A61K31/437;A61K31/454;A61K31/5377;A61K31/541;A61P1/04;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P7/04;A61P7/06;A61P9/10;A61P13/08;A61P15/00;A61P15/08;A61P17/00;A61P17/02;A61P19/02;A61P25/00;A61P25/04;A61P25/08;A61P25/22;A61P25/24;A61P29/00;A61P31/18;A61P35/00;A61P35/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D403/06;C07D417/06;C07D471/04 主分类号 C07D207/16
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