发明名称 |
Treatment of type 1 immune response-mediated inflammatory lung disease by modulation of ifn-gamma activity |
摘要 |
The present invention relates to preventing, or treating and/or reducing the severity or progression of Type 1 immune response-mediated inflammatory lung disease. More particularly, the present invention provides a method for preventing or treating chronic obstructive pulmonary disease (COPD), severe asthma, sarcoidosis, berylliosis or cystic fibrosis by neutralizing or reducing IFNgamma bioactivity which can be achieved either by in vivo administration of IFNgamma neutralizing molecules or by in vivo immunization with pharmaceutical compositions comprising immunogenic IFNgamma proteins or IFNgamma-derived (poly)peptides or their corresponding nucleic acid sequences.
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申请公布号 |
US2007031377(A1) |
申请公布日期 |
2007.02.08 |
申请号 |
US20050550175 |
申请日期 |
2005.11.10 |
申请人 |
DEPRAETERE STANY;LORRE KATRIEN;BUYSE MARIE-ANGE |
发明人 |
DEPRAETERE STANY;LORRE KATRIEN;BUYSE MARIE-ANGE |
分类号 |
A61K38/21;A61K39/00;A61K39/395;A61P11/00;A61P37/02;A61P37/08;C07K16/24 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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