发明名称 |
3R-3R' Stereoisomer of zeaxanthin for treating macular degeneration in humans |
摘要 |
In the present invention, there are described methods and formulations for preparing and purifying the 3R-3R' stereoisomer of zeaxanthin as a sole detectable isomer for use as a medicament or vitamin by humans, specifically for the treatment of patients suffering from macular degeneration. Zeaxanthin preparations containing only the desired 3R-3R' stereoisomer can be produced by a strain of Flavobacterium multivorum (ATCC accession number 55238). After synthesis using microbial fermentation, the zeaxanthin can be concentrated to a level of 5 to 20 percent by weight using simple and inexpensive means such as solvent extraction. It can also be purified to much higher levels by other methods if desired. |
申请公布号 |
CZ297575(B6) |
申请公布日期 |
2007.02.07 |
申请号 |
CZ19980001309 |
申请日期 |
1996.10.30 |
申请人 |
ZEA VISION, LLC |
发明人 |
GARNETT KEVIN M.;GIERHART DENNIS L.;GUERRA-SANTOS LUIS H. |
分类号 |
A61K31/047;C12P23/00;A23L1/30;A61F9/00;A61K9/107;A61K9/14;A61K9/20;A61K9/48;A61K31/015;A61K31/07;A61P27/02;C12R1/20 |
主分类号 |
A61K31/047 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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