发明名称 |
SYNTHESIS OF 2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-10H-THIENO[2, 3-B][1,5]BENZODIAZEPINE AND SALTS THEREOF |
摘要 |
<p>The invention belongs to the field of organic chemistry and relates to a new process for the purification of olanzapine comprising preparation of acid addition salts of olanzapine and transformation thereof into a pharmaceutically acceptable pure and discoloured final product. The present invention also relates to new processes for the preparation of pure olanzapine.</p> |
申请公布号 |
EP1749010(A2) |
申请公布日期 |
2007.02.07 |
申请号 |
EP20050716177 |
申请日期 |
2005.03.17 |
申请人 |
LEK PHARMACEUTICALS D.D. |
发明人 |
MESAR, TOMAZ;COPAR, ANTON;STURM, HUBERT;LUDESCHER, JOHANNES |
分类号 |
C07D495/04 |
主分类号 |
C07D495/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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