| 摘要 |
<p>The present invention refers to a process of manufacturing a compound of formula (Ia):
said process comprising:
(i) contacting a compound of formula (III):
with a compound of formula (IV):
in the presence of a palladium catalyst, methanol and hydrogen gas,
said step (i) being conducted preferably under basic conditions with acetic acid added once the consumption of the hydrogen gas has ceased.</p> |
