| 发明名称 |
Virus vectors and methods of making and administering the same |
| 摘要 |
The present invention provides genetically-engineered parvovirus capsids and viruses designed to introduce a heterologous gene into a target cell. The parvoviruses of the invention provide a repertoire of vectors with altered antigenic properties, packaging capabilities, and/or cellular tropisms as compared with current AAV vectors.
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| 申请公布号 |
US7172893(B2) |
申请公布日期 |
2007.02.06 |
| 申请号 |
US20020205942 |
申请日期 |
2002.07.26 |
| 申请人 |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
RABINOWITZ JOSEPH E.;SAMULSKI RICHARD JUDE;XIAO WEIDONG |
| 分类号 |
C12N7/00;C12N15/09;A01N63/00;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61P3/00;A61P3/10;A61P7/00;A61P11/00;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P31/18;A61P35/00;C07K14/015;C07K19/00;C12N1/11;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/01;C12N7/02;C12N15/74;C12N15/864;C12Q1/70 |
主分类号 |
C12N7/00 |
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