摘要 |
The present invention features rifamycin analogs that can be used as therapeutics for treatics or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25- position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3'- hydrxyl analogs, and/or various fused ring systems with the benzene ring at the 4', 5' or 5', 6' positions. ® KIPO & WIPO 2007
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