| 发明名称 |
Purification process for bacterial cytolysin |
| 摘要 |
The present invention relates to a method for purifying bacterial cytolysins such as pneumococcal pneumolysin. A single chromatography step produces excellent purification of the cytolysin by binding soluble aggregated cytolysin to a hydrophobic interaction chromatography material in the presence of detergent and high salt.
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| 申请公布号 |
US2007026010(A1) |
申请公布日期 |
2007.02.01 |
| 申请号 |
US20050549064 |
申请日期 |
2005.09.13 |
| 申请人 |
BIEMANS RALPH;GORAJ KARINE;MERTERS EMMANUEL;VANDERCAMMEN ANNICK |
发明人 |
BIEMANS RALPH;GORAJ KARINE;MERTERS EMMANUEL;VANDERCAMMEN ANNICK |
| 分类号 |
A61K39/102;A61K39/09;A61K39/385;C07H21/04;C07K1/16;C07K1/20;C07K14/285;C07K14/315;C12N1/21;C12N15/74;C12P21/00 |
主分类号 |
A61K39/102 |
| 代理机构 |
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