| 摘要 |
The present invention uses NF-?B as target point, and utilizes the NF-?B inhibitor to treat several diseases of mammal, e.g. virusinfection, cancer, chronic inflammation and autoimmune diseases. The said inhibitor includes the compounds and derivates which can inhibit NF-?B, such as quinazoline derivative, celastrol, phenylethyl caffeiatc, (E)3-((4-methylphenyl) ulfonyl)-2-acrylonitrile, Rocaglamide and 7-methoxy-5,11,12-trihydroxy-benzofuran coumarin. They can be used alonely or be combined with known clinical treatment to treat viral diseases, especially viral infection caused by retrovirus and AIDS caused by HIV, cancer, chronic inflammation and autoimmune diseases. |
