Modified fusion proteins of transferring and therapeutic proteins or peptides including, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
申请公布号
WO2006049983(A3)
申请公布日期
2007.02.01
申请号
WO2005US38531
申请日期
2005.10.27
申请人
BIOREXIS PHARMACEUTICAL CORPORATION;PRIOR, CHRISTOPHER, P.;SADEGHI, HOMAYOUN;BALLANCE, DAVID, J.;TURNER, ANDREW
发明人
PRIOR, CHRISTOPHER, P.;SADEGHI, HOMAYOUN;BALLANCE, DAVID, J.;TURNER, ANDREW