发明名称 |
VERFAHREN ZUR IDENTIFIZIERUNG NEUARTIGER GENE, DIE BEI DER REGULATION DER ANGIOGENESE EINER ROLLE SPIELEN, ANALYSE DIESER GENE SOWIE IHRE VERWENDUNG ZU THERAPEUTISCHEN ZWECKEN |
摘要 |
A process for identifying genes coding for cellular constituents involved in regulating angiogenesis including culturing endothelial cells on an extracellular matrix protein according to at least four different types of conditions: a reference condition, an angiogenesis promoting condition, an angiogenesis inhibiting condition, and a control condition; isolating messenger RNAs stemming from cells cultured according to the different conditions; and comparing at the qualitative and/or quantitative level, different messenger RNA populations to identify messenger RNAs stemming exclusively or in a particularly elevated quantity from cell cultures under conditions stimulating and/or inhibiting angiogenesis, the messenger RNAs corresponding to the genes coding for the cellular constituents involved in regulating angiogenesis. |
申请公布号 |
DE60029110(T2) |
申请公布日期 |
2007.02.01 |
申请号 |
DE2000629110T |
申请日期 |
2000.09.20 |
申请人 |
GENE SIGNAL INTERNATIONAL SA |
发明人 |
AL-MAHMOOD, SALMAN |
分类号 |
C12Q1/68;G01N33/50;A61K31/7088;A61K38/18;A61K48/00;A61P9/00;A61P9/10;A61P19/02;A61P27/02;A61P35/00;C12N5/02;C12N15/09;G01N33/53;G01N33/566 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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