| 发明名称 |
SUBSTITUTED PYRIDINONE AS MODULATOR OF P38 MAP KINASE |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a new compound useful as a modulator of a P38 MAP kinase. <P>SOLUTION: The compound of the formula (wherein R<SB>1</SB>is an alkyl which may arbitrarily be substituted, or the like; R<SB>2</SB>is an arylalkoxy which may arbitrarily be substituted; R<SB>3</SB>is H, a halogen, an alkoxycarbonyl which may be arbitrarily substituted, or the like; R<SB>4</SB>is H or an alkyl which may arbitrarily be substituted; and R<SB>5</SB>is an aryl which may arbitrarily be substituted, an arylalkyl or the like) and a pharmaceutically acceptable salt thereof are provided. <P>COPYRIGHT: (C)2007,JPO&INPIT</p> |
| 申请公布号 |
JP2007023053(A) |
申请公布日期 |
2007.02.01 |
| 申请号 |
JP20060263778 |
申请日期 |
2006.09.28 |
| 申请人 |
PHARMACIA CORP |
发明人 |
DEVADAS BALEKUDRU;WALKER JOHN;SELNESS SHAUN R;BOEHM TERRI L;DURLEY RICHARD C;DEVRAJ RAJESH;HICKORY BRIAN S;RUCKER PAUL V;JEROME KEVIN D;MADSEN HEATHER M;ALVIRA EDGARDO;PROMO MICHELE A;BLEVIS-BAL RADHIKA M;MARRUFO LAURA D;HITCHCOCK JEFF;OWEN THOMAS;NAING WIN;XING LI;SHIEH HUEY S;SAMBANDAM ARUNA;LIU SHUANG;SCOTT IAN L;MCGEE KEVIN F |
| 分类号 |
C07D213/64;A61K31/4412;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4535;A61K31/4545;A61K31/455;A61K31/4725;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61P1/02;A61P1/04;A61P1/16;A61P3/10;A61P7/02;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P15/08;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/06;A61P19/08;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/04;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/12;A61P31/16;A61P31/18;A61P31/22;A61P33/02;A61P33/06;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D213/69;C07D213/70;C07D213/74;C07D213/75;C07D213/79;C07D213/80;C07D213/82;C07D213/84;C07D213/85;C07D215/22;C07D401/04;C07D401/06;C07D401/10;C07D401/12;C07D401/14;C07D405/04;C07D405/06;C07D405/12;C07D405/14;C07D409/06;C07D409/14;C07D413/10 |
主分类号 |
C07D213/64 |
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