发明名称 Polysubstituted 1,1-pyridylamioncyclopropanamine compounds
摘要 A compound selected from those of formula (I): wherein: n represents an integer from 1 to 6 inclusive, R<SUB>1 </SUB>and R<SUB>2 </SUB>represent a hydrogen atom, a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group or an aryl-(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group, R<SUB>3 </SUB>and R<SUB>4 </SUB>represent a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group, R<SUB>5 </SUB>and R<SUB>6 </SUB>represent a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, halogen, hydroxy, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy, cyano, nitro, (C<SUB>2</SUB>-C<SUB>6</SUB>)acyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxycarbonyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)trihaloalkyl or (C<SUB>1</SUB>-C<SUB>6</SUB>)-trihaloalkoxy group or an optionally substituted amino group, R<SUB>7 </SUB>represents a hydrogen atom, a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group or an arylalkyl group, its enatiomers, diastereoisomers and additional salts thereof with a pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful in the treatment of conditions requiring a specific nicotinic ligand of alpha4beta2 receptors.
申请公布号 US2007027192(A1) 申请公布日期 2007.02.01
申请号 US20060493155 申请日期 2006.07.26
申请人 GOLDSTEIN SOLO;GUILLONNEAU CLAUDE;CHARTON YVES;LOCKHART BRIAN;LESTAGE PIERRE 发明人 GOLDSTEIN SOLO;GUILLONNEAU CLAUDE;CHARTON YVES;LOCKHART BRIAN;LESTAGE PIERRE
分类号 A61K31/44;A61P25/00;C07D213/72;C07D213/74 主分类号 A61K31/44
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