发明名称 |
METHODS OF TARGETING BAFF |
摘要 |
The present disclosure provides compositions and methods relating to the structure of BAFF in solution. The disclosure includes BAFF 60-mers, BAFF trimers, methods of making BAFF 60-mers and BAFF trimers, antibodies that preferentially bind one form or the other, and methods of identifying or evaluating a compound on the basis of its relative binding to or activity towards a BAFF 60-mer and a BAFF trimer. The disclosure also provides computer-based systems and methods relating to BAFF structures. |
申请公布号 |
WO2007014390(A2) |
申请公布日期 |
2007.02.01 |
申请号 |
WO2006US29767 |
申请日期 |
2006.07.27 |
申请人 |
BIOGEN IDEC MA INC.;CACHERO, TERESA;WHITTY, ADRIAN;LUGOVSKOY, ALEXEY |
发明人 |
CACHERO, TERESA;WHITTY, ADRIAN;LUGOVSKOY, ALEXEY |
分类号 |
G01N33/531 |
主分类号 |
G01N33/531 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|