发明名称 |
Non-imidazole alkylamines as histamine H3-receptor ligands and their therapeutic applications |
摘要 |
Use of a compound of formula (A), wherein: W is a residue which imparts antagonistic and/or agonistic activity at histamine H<SUB>3</SUB>-receptors when attached to an imidazole ring in 4(5) position; R<SUP>1 </SUP>and R<SUP>2 </SUP>may be identical or different and represent each independently a lower alkyl or cycloalkyl, or taken together with the nitrogen atom to which they are attached, a saturated nitrogen-containing ring (i) as defined, a non-aromatic unsaturated nitrogen-containing ring (ii) as defined, a morpholino group, or a N-substituted piperazino group as defined for preparing medicaments acting as antagonists and/or agonists at the H<SUB>3</SUB>-receptors of histamine.
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申请公布号 |
US7169928(B2) |
申请公布日期 |
2007.01.30 |
申请号 |
US20040856838 |
申请日期 |
2004.06.01 |
申请人 |
SOCIETE CIVILE BIOPROJECT |
发明人 |
SCHWARTZ JEAN-CHARLES;ARRANG JEAN-MICHEL;GARBARG MONIQUE;LECOMTE JEANNE-MARIE;LIGNEAU XAVIER;SCHUNACK WALTER G.;STARK HOLGER;GANELLIN CHARON ROBIN;LEURQUIN FABIEN;ELZ SIGURD |
分类号 |
C07D211/56;C07D295/02;A61K31/135;A61K31/136;A61K31/138;A61K31/275;A61K31/40;A61K31/4245;A61K31/428;A61K31/44;A61K31/445;A61K31/4453;A61K31/4468;A61K31/4523;A61K31/4545;A61K31/4709;A61K31/495;A61K31/496;A61K31/506;A61K31/5375;A61K31/5377;A61K31/55;A61P1/00;A61P1/04;A61P3/04;A61P11/02;A61P11/06;A61P13/00;A61P15/00;A61P19/02;A61P21/00;A61P25/00;A61P25/06;A61P25/18;A61P25/24;A61P25/28;A61P29/00;A61P37/08;A61P43/00;C07C217/16;C07C217/18;C07C217/20;C07C217/22;C07C251/48;C07C255/54;C07D207/08;C07D207/18;C07D207/20;C07D211/14;C07D211/20;C07D211/58;C07D211/60;C07D211/62;C07D211/70;C07D213/74;C07D215/38;C07D215/46;C07D239/42;C07D271/06;C07D277/82;C07D295/03;C07D295/08;C07D295/088;C07D295/092;C07D295/096;C07D295/13;C07D295/18;C07D295/185 |
主分类号 |
C07D211/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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