发明名称 Guanidinium transport reagents and conjugates
摘要 Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
申请公布号 US7169814(B2) 申请公布日期 2007.01.30
申请号 US20020318278 申请日期 2002.12.11
申请人 CELLGATE, INC. 发明人 ROTHBARD JONATHAN B.;WENDER PAUL A.;PATTABIRAMAN KANAKA;PELKEY ERIN T.;JESSOP THEODORE C.
分类号 A61K31/155;A61K31/395;A61K31/4188;A61K47/48;A61P29/00;A61P31/04;A61P31/10;A61P35/00;A61P43/00 主分类号 A61K31/155
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