发明名称 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
摘要 Novel C-13<SUP>2</SUP>-COXR<SUB>1</SUB>, C-17<SUP>2</SUP>-COXR<SUB>2 </SUB>and C-13<SUP>2</SUP>-COXR<SUB>1</SUB>, C-17<SUP>2</SUP>-COXR<SUB>1 </SUB>derivatives of chlorophyll and bacteriochlorophyll compounds are provided wherein X is O, S or N and R<SUB>1 </SUB>and R<SUB>2</SUB>, the same or different, may be an optionally substituted hydrocarbyl, amino acid, peptide, protein or saccharide radical. The compounds are for use in photodynamic therapy (PDT), for diagnosis of tumors, and for killing cells and infectious agents such as bacteria and virus, both in biological products and in living tissues.
申请公布号 US7169753(B2) 申请公布日期 2007.01.30
申请号 US20020148552 申请日期 2002.11.06
申请人 YEDA RESEARCH AND DEVELOPMENT CO. LTD. 发明人 SCHEER HUGO;KAMMHUBER NINA;SCHERZ AVIGDOR;BRANDIS ALEXANDER;SALOMON YORAM
分类号 A61K38/00;A61K31/409;A61K31/555;A61K31/7052;A61K41/00;A61K49/00;A61P31/04;A61P31/12;A61P35/00;C07B61/00;C07D487/22;C07H13/04;C07H13/10;C07H15/26;C07K1/20;C07K2/00 主分类号 A61K38/00
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