| 摘要 |
<p>The invention relates to a method of analysing materials, in particular biological tissues, comprising the detection of beta -rays, particularly positron rays, that are emitted by the material, specifically a biological tissue, which is radioactive, preferably radiolabelled with pharmaceutical radio compounds in the case of a biological tissue. The invention is essentially intended to improve the performances of intraoperative positron probes, in terms of miniaturisation and increasing sensitivity and selectivity in respect of useful detection positrons. The inventive method comprises the following steps consisting in: placing at least two opposing detectors on either side of a mass of material to be analysed; detecting, in coincidence in each detector, a Compton electron generated, by means of the Compton scattering mechanism, from the interaction with one of the two incident photons resulting from the annihilation between a positron emitted by the mass of material to be analysed and an electron; selecting the coincident detection signals, namely the signals for each of which the detection of a Compton electron in a detector coincides temporally with the detection of a Compton electron in the other opposing detector; counting the selected signals such as to gather information that is representative of the quantity of positrons emitted by the mass of material to be analysed; and, optionally, communicating the aforementioned information to the user. The invention also relates to the device [intraoperative (clamp) probe] used to implement the method. The invention is suitable for the identification and excision of tumours.</p> |
