| 发明名称 |
Substituted benzopyrans as selective estrogen receptor-beta agonists |
| 摘要 |
Disclosed are compounds of formula (I) wherein: R1, R2, and R3 are each independently H, alkyl, OH, alkoxy, halo or CF3; R5 is H or alkyl; Y1, Y2 and Y3 are each independently H or alkyl; and G is -CH2-, -CH2-CH2 -, or -CH2-CH2-CH2-. Also disclosed is the use of compounds of formula (I) in the manufacture of a medicament for treating prostate cancer, benign prostate hyperplasia or an estrogen receptor beta mediated condition.
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| 申请公布号 |
NZ531850(A) |
申请公布日期 |
2007.01.26 |
| 申请号 |
NZ20020531850 |
申请日期 |
2002.11.07 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
DODGE, JEFFREY ALAN;KRISHNAN, VENKATESH GARY;LUGAR, CHARLES WILLIS;NEUBAUER, BLAKE LEE;NORMAN, BRYAN HURST;PFEIFER, LANCE ALLEN;RICHARDSON, TIMOTHY IVO |
| 分类号 |
A61K31/353;A61P1/04;A61P9/00;A61P11/00;A61P13/02;A61P13/08;A61P15/00;A61P19/10;A61P25/00;A61P25/28;A61P35/00;A61P43/00;C07D311/80;C07D311/94;C07D491/02;C07D493/02;(IPC1-7):C07D311/60;A61K31/352 |
主分类号 |
A61K31/353 |
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