METHOD FOR IMMOBILIZING LIVE CELL AND SENSOR FOR MEASURING ACTIVATING FUNCTION OF LIVE CELL

摘要

PROBLEM TO BE SOLVED: To provide a method for immobilizing a live cell especially suitable for evaluating activating functions of the live cell utilizing plasmon resonance and having an excellent sticking tendency in relation to the method for immobilizing the live cell in order to immobilize the live cell on the surface of a solid phase. SOLUTION: The method for immobilizing the live cell comprises immobilizing the live cell through a live cell immobilizing material composed of an organic compound having a thiol group and an amino group or an organic compound having a disulfide group and amino group on the surface of the solid phase. The live cell is preferably immobilized under physiological environments and the surface of the solid phase is preferably a metal surface having affinity for the thiol group or disulfide group. The organic compound is preferably an aminoalkanethiol or a disulfide type compound in which the two molecules thereof are bound. A sensor for measuring the activating functions of the live cell in which the live cell is immobilized on the tip of an optical fiber suitable for evaluating the activating functions of the live cell can be composed by utilizing the method for immobilizing the live cell. COPYRIGHT: (C)2007,JPO&INPIT