发明名称 Method of stabilizing antibody and stabilized solution-type antibody preparation
摘要 The present invention provides a method of suppressing the formation of a soluble association of an antibody in a solution; a method of suppressing the formation of a chemically degraded product of an antibody in a solution; and a method of stabilizing an antibody in a solution. The present invention also provides a solution-type antibody preparation in which the formation of a soluble association is suppressed; a solution-type antibody preparation in which the formation of a chemically degraded product is suppressed; a solution-type antibody preparation in which the formation of a soluble association, the formation of a chemically degraded product and the formation of an insoluble aggregate are suppressed; an agent for suppressing the formation of a soluble association of an antibody; an agent for suppressing the formation of a chemically degraded product of an antibody; and a stabilizing agent for an antibody.
申请公布号 US2007020255(A1) 申请公布日期 2007.01.25
申请号 US20040574016 申请日期 2004.10.01
申请人 KYOWA HAKKO KOGYO CO., LTD. 发明人 UENO YUJI;KAYASHITA TAKASHI;ISHIHARA ATSUSHI;NAKAKURA MASASHI;YAMAUCHI KYOKO
分类号 A61K39/395;A61K9/00;A61K9/08;A61K47/12;A61K47/18;C07K16/00;C07K16/18;C07K16/46 主分类号 A61K39/395
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