METHOD FOR HIGH-THROUGHPUT SCREENING

摘要

This invention relates to methods for assessing platelet activation. Such methods can be used to diagnose whether a subject has an increased risk of bleeding or thrombosis, to screen for compounds that are agonists or antagonists of platelet activation, or to screen for defective platelets. The invention provides a method for assessing platelet activation, which comprises: stimulating platelets in a platelet sample to cause activation of the platelets; capturing activated platelets from the platelet sample in preference to resting platelets; and detecting the captured activated platelets.