The invention relates to a method for producing the racemic active ingredient Nebivolol, according to which diastereomer cyanhydrins are produced and separated, and the separated diastereomers are coupled together following a transformation, preferably a partial or full reduction of the cyano group or a Pinner saponification.
申请公布号
WO2007009143(A2)
申请公布日期
2007.01.25
申请号
WO2006AT00303
申请日期
2006.07.17
申请人
PHARMACON - FORSCHUNG UND BERATUNG GMBH;NOE, CHRISTIAN, R.;JASIC, MUHAMED;KOLLMANN, HERMANN;LACHMANN, BODO
发明人
NOE, CHRISTIAN, R.;JASIC, MUHAMED;KOLLMANN, HERMANN;LACHMANN, BODO