发明名称 |
PROCESS FOR THE PRODUCTION OF 3-OXO-PREGN-4-ENE-21,17-CARBOLACTONES BY THE METAL-FREE OXIDATION OF 17-(3-HYDROXYPROPYL)-3,17-DIHYDROXYANDROSTANES |
摘要 |
This invention relates to processes for the production of 3-oxo-pregnane-21,17-carbolactones of formula (II) as well as 3-oxo-pregn-4-ene-21,17-carbolactones of formula (III) by the metal-free oxidation of 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanes of formula (I). In addition, the invention relates to the dichloromethane hemisolvate of 6ß ,7ß; 15ß,16ß-dimethylene-3-oxo-17a-pregnan-5ß-ol-21,17-carbolactone (IV) as such as well as to a process for the production of drospirenone. |
申请公布号 |
WO2007009821(A1) |
申请公布日期 |
2007.01.25 |
申请号 |
WO2006EP07287 |
申请日期 |
2006.07.20 |
申请人 |
SCHERING AKTIENGESELLSCHAFT;SEILZ, CARSTEN;SEBA, HARTMUT |
发明人 |
SEILZ, CARSTEN;SEBA, HARTMUT |
分类号 |
C07J53/00 |
主分类号 |
C07J53/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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