METHODS AND COMPOSITIONS FOR EXTRACTING MEMBRANE PROTEINS

摘要

The present invention provides methods and compositions for the isolation and use of membrane proteins and other membrane associated molecules (e.g., peptides, carbohydrates, lipids, or combinations thereof). In particular, the present invention provides amphiphilic polymer compositions and methods of using the compositions to solubilize, enrich and isolate components of biological membranes, including membrane proteins, while retaining function and/or activity of the component.