发明名称 |
ANTIARRHYTHMIC PRECURSOR COMPOUNDS, METHODS OF SYNTHESIS AND METHODS OF USE |
摘要 |
The invention comprises compounds of Formula 1: wherein, R<SUB>1</SUB> is independently H or halogen; R<SUB>2</SUB> is, for example, H or -R<SUB>10</SUB>-NR<SUB>11</SUB>R<SUB>12</SUB>, and wherein R<SUB>10</SUB> is C1-C6 alkyl, and R<SUB>11</SUB> and R<SUB>12</SUB> are independently H, C<SUB>1</SUB>-C<SUB>4</SUB> alkyl, and hydrates, solvates, salts and tautomers thereof. The invention further comprises methods for making the compounds of the invention and methods for making compounds useful in the treatment or prevention of cardiac arrhythmia from the compounds of the invention. |
申请公布号 |
WO2007011835(A2) |
申请公布日期 |
2007.01.25 |
申请号 |
WO2006US27599 |
申请日期 |
2006.07.14 |
申请人 |
ARYX THERAPEUTICS;DRUZGALA, PASCAL;TIEN, JIEN-HEH, J.;COOPER, ART;BECKER, CYRUS |
发明人 |
DRUZGALA, PASCAL;TIEN, JIEN-HEH, J.;COOPER, ART;BECKER, CYRUS |
分类号 |
C07D493/04;A61K31/35 |
主分类号 |
C07D493/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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