发明名称 |
PRODUCTION OF AN ASPOROGENIC STRAIN OF BACILLUS LICHENIFORMIS AND ITS USE FOR THE PRODUCTION OF KERATINASE |
摘要 |
A recombinant bacteria and methods of making and using the same are provided. The recombinant bacteria is a recombinant Bacillus having an inactive endogenous spoIIAC gene, with said recombinant Bacillus producing greater quantities of keratinase than a corresponding wild-type Bacillus that does not have said inactive endogenous spoIIAC gene inserted therein. The Bacillus can be Bacillus licheniformis or Bacillus subtilis. The recombinant Bacillus can be a sporulation-deficient Bacillus. A feed additive including keratinase derived from the recombinant Bacillus having an inactive endogenous spoIIAC gene and methods of inactivating an infectious prion protein are also provided. |
申请公布号 |
WO2007011410(A1) |
申请公布日期 |
2007.01.25 |
申请号 |
WO2005US39583 |
申请日期 |
2005.10.28 |
申请人 |
NORTH CAROLINA STATE UNIVERSITY;SHIH, JASON C.H. |
发明人 |
SHIH, JASON C.H. |
分类号 |
C12N9/56 |
主分类号 |
C12N9/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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