A single stranded oligonucleotide having substantially no secondary structure and formed of nucleotide residues wherein two or more internal nucleotide residues are labelled with a fluorophore without an associated quencher. Typically at least two of the nucleotide residues labelled with a fluorophore are separated by at least two unlabelled nucleotide residues. The oligonucleotides are useful in the investigation of target polynucleotide sequences.
申请公布号
WO2007010268(A2)
申请公布日期
2007.01.25
申请号
WO2006GB02719
申请日期
2006.07.20
申请人
LGC LIMITED;MCDOWELL, DAVID, GORDON;FRENCH, DAVID, JOHN