发明名称 MEDICAL DEVICES AND COATINGS THEREFOR
摘要 A coating for a medical device, the device generally being of the type which is to be used internally in a subject, includes a transglutaminase (TGase) inhibitor. The Tgase inhibitor effectively prevents the activity of any Tgase involved in clot formation or clot stability. Preferably, the transglutaminase inhibitor is a factor XIIIa inhibitor. The coating may be prepared by suitable processes such as esterification. The coating may be immobilized on a suitable medical device in a number of ways and is preferably included in a TGase inhibitor containing polymer. The coating may also include a suitable antimicrobial agent.
申请公布号 WO2007010201(A2) 申请公布日期 2007.01.25
申请号 WO2006GB02587 申请日期 2006.07.12
申请人 ASTON UNIVERSITY;LAMBERT, PETER, A.;GRIFFIN, MARTIN;COLLIGHAN, RUSSELL;RATHBONE, DANIEL, LEE 发明人 LAMBERT, PETER, A.;GRIFFIN, MARTIN;COLLIGHAN, RUSSELL;RATHBONE, DANIEL, LEE
分类号 A61L33/14;A61L27/34;A61L27/54;A61L31/10;A61L31/16 主分类号 A61L33/14
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