发明名称 NEK8S AS MODIFIERS OF THE PTEN/AKT PATHWAY AND METHODS OF USE
摘要 Human NEK8 genes are identified as modulators of the PTEN/AKT pathway, and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT, comprising screening for agents that modulate the activity of NEK8 are provided.
申请公布号 WO2006099183(A3) 申请公布日期 2007.01.25
申请号 WO2006US08677 申请日期 2006.03.10
申请人 EXELIXIS, INC;BRACE, ARTHUR;BLAKE, ROBERT, A.;FRIEDMAN, LORI, S.;BJERKE, LYNN, MARGARET;WARD, KEVIN;NIETO-BERGMAN, SUSANA 发明人 BRACE, ARTHUR;BLAKE, ROBERT, A.;FRIEDMAN, LORI, S.;BJERKE, LYNN, MARGARET;WARD, KEVIN;NIETO-BERGMAN, SUSANA
分类号 G01N33/53 主分类号 G01N33/53
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