发明名称 |
MDA-7 PROTEIN VARIANTS HAVING ANTIPROLIFERATIVE ACTIVITY |
摘要 |
The invention relates to the mda-7 gene, its encoded protein and fragments of the proteins. Several of these fragments of the MDA-7 protein exhibit antiproliferative activity and/or inhibited the activity of intact MDA-7. Accordingly, the invention provides, among other things, for methods and compositions that may be used in the treatment of disorders of cell proliferation, including cancer.
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申请公布号 |
WO2006060680(A3) |
申请公布日期 |
2007.01.25 |
申请号 |
WO2005US43673 |
申请日期 |
2005.12.02 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;FISHER, PAUL, B.;GUPTA, PANKAJ |
发明人 |
FISHER, PAUL, B.;GUPTA, PANKAJ |
分类号 |
A61K48/00;G01N1/10 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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地址 |
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