Compositions and methods of treating tumors

摘要

Methods of treating an individual who has an erb B protein mediated tumor is disclosed. Methods of preventing erb B protein mediated tumors in an individual are disclosed. The methods comprise adminstering to the individual a nucleic acid molecule that encodes a protein that dimerizes with an erb B protein and that is deficient in tyrosine kinase activity. Composition that comprise such nucleic acid molecules including pharmaceutical compositions are disclosed.