| 发明名称 |
ANTIBODY MUTANTS |
| 摘要 |
<p>Antibody mutants of species-dependent antibodies are disclosed which have at least one amino acid substitution in a hypervariable region of species-dependent antibody and a binding affinity for an antigen from a nonhuman mammal which is at least about 10 fold stronger than the binding affinity of the species-dependent antibody for the antigen.</p> |
| 申请公布号 |
EP0946727(B1) |
申请公布日期 |
2007.01.24 |
| 申请号 |
EP19970947371 |
申请日期 |
1997.10.29 |
| 申请人 |
GENENTECH, INC. |
发明人 |
JARDIEU, PAULA, M.;PRESTA, LEONARD, G. |
| 分类号 |
C12N15/13;A61K38/00;C07K14/705;C07K16/00;C07K16/28;C07K16/46;C12N1/20 |
主分类号 |
C12N15/13 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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