摘要 |
A method for producing optically active IHOG useful for the production of monatin, a method for producing optically active monatin, and aldolase used for the methods are provided. 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity which is useful as an intermediate in the synthesis of optically active monatin may be synthesized from indole pyruvic acid and pyruvic acid (or oxaloacetic acid). |