Uses of perfluorinated carboylic acid derivatives for the manufacture of a medicament for the modulation of body mass

摘要

The molecules of formula I are useful in treating diabetes, obesity, hypercholesterolaemia, hyperlipidaemia, cancer, inflammation or other conditions in which modulation of lipid or eicosanoid status or function may be desirable.
Formula I:
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ Z 1 -X-Z 2 €ƒ€ƒ€ƒ€ƒ€ƒI
wherein
Z 1 represents -CO 2 H or a derivative thereof;
Z 2 represents F, H, -CO 2 H or a derivative thereof; and
X represents fluorinated alkylene;
or a solvate thereof,
for example a perfluorinated fatty acid or derivative thereof.