| 摘要 |
The method for producing resorbable or degradable polymeric medical devices by applying compressive forces on solid polymeric objects containing liquid or solid additives, is characterized in that: A) the additives are able to promote the slip-page of the polymeric objects through the forming device, facilitate transient chain mobility and promote chain orientation; B) said additives are present in an amount of 0.005 to 20% of the dry weight of said polymeric objects; C) the solubility parameters of said additives being selected in such a way that after absorbing by said polymeric objects the additives do not dissolve more than 0.01 to 1% of the total mass of said polymeric objects; D) said applying of compressive forces is performed minimally at a temperature of Tmin=Tg−50° C., Tg being the glass transition temperature of the polymer the said object is made of polymer; and E) said applying of compressive forces is performed maximally at a temperature Tmax=Tm−5° C., Tm being the melting peak temperature of the polymer the said object is made of said polymer objects. |
