发明名称 Aminoindazole derivatives as medicaments and pharmaceutical compositions including them
摘要 The present invention relates to novel derivatives of general formula (I) in which R3 is a (1-6C)alkyl, aryl, aryl(1-6C)alkyl, heteroaryl, heteroaryl(1-6C)alkyl, aryl or heteroaryl fused to a (1-10C)cycloalkyl, heterocycle, heterocycloalkyl, cycloalkyl, adamantyl, polycycloalkyl, alkenyl, alkynyl, CONR1R2, COOR1, SO<SUB>2</SUB>R1, C(-NH)R1 or C(-NH)NR1 radical; R5 and R6 are, independently of one another, chosen from the following radicals: halogen, CN, NO<SUB>2</SUB>, NH<SUB>2</SUB>, OH, COOH, C(O)OR8, -O-C(O)R8, NR8R9, NHC(O)R8, C(O)NR8R9, NHC(S)R8, C(S)NR8R9, SR8, S(O)R8, SO<SUB>2</SUB>R8, NHSO<SUB>2</SUB>R8, SO<SUB>2</SUB>NR8R9, -O-SO<SUB>2</SUB>R8, -SO<SUB>2</SUB>-O-R8, trifluoromethyl, trifluoromethoxy, (1-6C)alkyl, (1-6C)alkoxy, aryl, aryl(1-6C)alkyl, heteroaryl, heteroaryl(1-6C)alkyl, heterocycle, cycloalkyl, alkenyl, alkynyl, adamantyl or polycycloalkyl.
申请公布号 US7166629(B2) 申请公布日期 2007.01.23
申请号 US20030654703 申请日期 2003.09.04
申请人 AVENTIS PHARMA S.A. 发明人 LESUISSE DOMINIQUE;DUTRUC-ROSSET GILLES;HALLEY FRANCK;BABIN DIDIER;ROONEY THOMAS
分类号 A61K31/416;A61P3/00;A61P9/00;A61P9/12;A61P25/16;A61P25/28;A61P35/00;A61P37/00;A61P37/04;C07D231/56;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12 主分类号 A61K31/416
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