摘要 |
<p>Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein XI, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.</p> |
申请人 |
OSI PHARMACEUTICALS, INC. |
发明人 |
ARNOLD, LEE, D.;MULVIHILL, MARK, JOSEPH;LI, AN-HU;CREW, ANDREW PHILIP;NIGRO, ANTHONY;CESARIO, CARA;LAUFER, RADOSLAW;ZHANG, TAO;HONDA, AYAKO;SUN, YINGCHUAN;FOREMAN, KENNETH;STEINIG, ARNO, G;COATE, HEATHER;DONG, HANQING;MULVIHILL, KRISTEN MICHELLE;PANICKER, BIJOY;WENG, QINGHUA;WERNER, DOUGLAS S.;WYLE, MICHAEL J. |