发明名称 PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION
摘要 The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of : a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent ; and optionally b) isolating the obtained sulphoxide of formula (I), wherein n, Y, R1, R1a, R2 and R2a are as defined in claim 1. ® KIPO & WIPO 2007
申请公布号 KR20070009968(A) 申请公布日期 2007.01.19
申请号 KR20067007002 申请日期 2004.09.17
申请人 CEPHALON FRANCE (SAS) 发明人 REBIERE FRANCOIS;DURET GERARD;PRAT LAURENCE
分类号 C07C315/02;C07C317/44 主分类号 C07C315/02
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