发明名称 Benzimidazole compound
摘要 An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R<SUP>1 </SUP>and R<SUP>3 </SUP>may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R<SUP>2 </SUP>represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6 </SUP>and R<SUP>7 </SUP>represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W<SUP>1 </SUP>represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.
申请公布号 US2007015782(A1) 申请公布日期 2007.01.18
申请号 US20060403815 申请日期 2006.04.14
申请人 EISAI CO., LTD. 发明人 MIYAZAWA SHUHEI;SHINODA MASANOBU;KAWAHARA TETSUYA;WATANABE NOBUHISA;HARADA HITOSHI;IIDA DAISUKE;TERAUCHI HIROKI;NAGAKAWA JUNICHI;FUJISAKI HIDEAKI;KUBOTA ATSUHIKO;UEDA MASATO
分类号 A61K31/4747;A61K31/4439;C07D491/14 主分类号 A61K31/4747
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