COMPOSITIONS AND METHOD FOR INCREASING THE EFFICACY OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS
摘要
Compositions and methods for increasing the efficacy of an epidermal growth factor receptor-tyrosine kinase inhibitor are provided. The drugs are modified stereospecific epidermal growth factor receptor-tyrosine kinase inhibitors that upon modification are able to accumulate at higher levels in tumor cells thereby increasing the efficacy of the inhibitor.
申请公布号
WO2006110608(A3)
申请公布日期
2007.01.18
申请号
WO2006US13196
申请日期
2006.04.07
申请人
TRUSTEES OF DARTMOUTH COLLEGE;PETTY, JEFFREY, W.;DMITROVSKY, ETHAN