LIPOPHILIC DYE-BASED FRET ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY
摘要
Compositions useful for detecting Clostridial toxin activity comprising a cell that comprises a membrane-associated Clostridial toxin substrate comprising a first member of a fluorescence resonance energy transfer pair; and a Clostridial toxin recognition sequence including a cleavage site; and a membrane-associated second member of the FRET pair and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates.
申请公布号
WO2006107921(A3)
申请公布日期
2007.01.18
申请号
WO2006US12426
申请日期
2006.04.04
申请人
ALLERGAN, INC.;FERNANDEZ-SALAS, ESTER;STEWARD, LANCE, E.;AOKI, KEI, ROGER
发明人
FERNANDEZ-SALAS, ESTER;STEWARD, LANCE, E.;AOKI, KEI, ROGER