发明名称 |
HOMOEOLOGOUS REGION JUDGING METHOD BY HOMO JUNCTION FINGERPRINT METHOD, HOMOEOLOGOUS REGION JUDGING DEVICE, AND GENE SCREENING METHOD |
摘要 |
<p>[PROBLEMS] To provide a method for efficiently searching for a recessive disease gene without needing any pedigree analysis. [MEANS FOR SOLVING PROBLEMS] In a homoeologous region judging method, the following steps are conducted. It is judged whether or not the base constituting a polymorphic marker of a sample DNA of diploid or higher polyploidy is a homojunction. Homojunction region information representing the region of the sample DNA where polymorphic markers judged as homojunctions continue is acquired. If the continuous probability and/or continuous distance of the polymorphic markers contained in the homojunction region information satisfy a predetermined judgment condition, the homojunction region is judged as a homoeologous region. A homoeologous region judging device and a gene screening method for identifying a disease susceptibility gene from the judged homoeologous region are also provided.</p> |
申请公布号 |
WO2007007691(A1) |
申请公布日期 |
2007.01.18 |
申请号 |
WO2006JP313616 |
申请日期 |
2006.07.07 |
申请人 |
TOMY DIGITAL BIOLOGY CO., LTD.;SAITAMA MEDICAL UNIVERSITY;HAGIWARA, KOICHI |
发明人 |
HAGIWARA, KOICHI |
分类号 |
C12Q1/68;C12M1/00;C12N15/09;G06F19/00;G06F19/18;G06F19/22 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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