发明名称 |
Modified antibody fragments |
摘要 |
The present invention relates to a new class of antibody fragments including antibody Fab and Fab' fragments in which the heavy chain is not covalently bonded to the light chain and two or more effector molecules are attached to the fragment, of which at least one of said molecules is attached to a cysteine in the heavy or light chain constant region.
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申请公布号 |
US2007014802(A1) |
申请公布日期 |
2007.01.18 |
申请号 |
US20040562769 |
申请日期 |
2004.07.01 |
申请人 |
CELLTECH R & D LIMITED |
发明人 |
HEYWOOD SAM PHILIP;HUMPHREYS DAVID P. |
分类号 |
A61K39/395;C07H21/04;C07K16/00;C07K16/30;C12P21/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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