NOVEL 1H-INDOLE-PYRIDINECARBOXAMIDE AND 1H-INDOLE-PIPERIDINECARBOXAMIDE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

摘要

The invention relates to compounds of formula (I) in whichA represents a bivalent radical in which Z represents an oxygen atom or a sulfur atoms; R₆ represents a hydrogen atom, an alkyl, alkenyl, arylalkyl or polyhalogen alkyl group or a substituted linear or branched alkyl chain, ------- represents a single bond or a double bond; R₁, R₂, R₃, R₄ represent a hydrogen or halogen atom, an alkyl, alkoxy, hydroxy, cyano, nitro or polyhalogenoalkyl group, or an optionally substituted amino, alkenyl or a linear or branched alkyl chain substituted by one or more groups; R₅ represents a hydrogen atom, an alkyl, aminoalkyl or hydroalkyl group; X, Y represent a hydrogen atom or an alkyl group; R_a, R_b, R_c, R_d represent a hydrogen or halogen atom, an alkyl, hydroxy, alkoxy, cyano, nitro or polyhalogenoalkyl group, an optionally substituted amino, alkyl or a substituted linear or branched alkyl chain; Re represents a hydrogen atom or an alkyl, arylalkyl or alkenyl group or a substituted linear or branched alkyl chain, their enantiomers, diastereoisomers, N-oxides, as well as their pharmaceutically acceptable acid or base addition salts. The invention also relates to corresponding medicaments.