MULTI-TRANSDUCTION MECHANISM BASED MICROFLUIDIC ANALYTE SENSORS

摘要

In various aspects are provided a rnicrof luidic and/or nanofluidic sensor thab can provide an indication of the reliability of its measurement of the presence of an analyte in a sample under investigation, an analyte concentration in the sample under investigation, or both. The provided sensors and microfluidic devices utilize two transduction mechanisms from the same molecule to determine analyte presence, analyte concentration, or both. An analyte sensing molecule is used that can provide both fluorescence signal and electrochemical signal when an analyte is recognized by an analyte binding portion of the sensing molecule.