发明名称 |
COMPOSITIONS AND USE OF INFLAMMATION-20 (INF-20) GENE |
摘要 |
This invention relates to Inf-20, a novel apoptosis regulator, that in one embodiment is induced by TNF. The gene, designated inflammation-20 (Inf-20), encodes a polypeptide of 184 amino acids. In one embodiment Inf-20 comprises a conserved death effector domain (DED) that is capable of interacting with caspase-8, but not with Fas-associated death domain (FADD) protein. |
申请公布号 |
WO2005116189(A3) |
申请公布日期 |
2007.01.18 |
申请号 |
WO2005US15422 |
申请日期 |
2005.05.05 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;CHEN, YOUHAI, H.;SUN, HONGHONG;GONG, SHUNYOU |
发明人 |
CHEN, YOUHAI, H.;SUN, HONGHONG;GONG, SHUNYOU |
分类号 |
C07H21/02;C07H21/04;C07K14/00;C07K14/47;C12N5/02 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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