| 发明名称 |
AN EFFICIENT METHOD FOR PREPARING 3-ARYLOXY-3- ARYLPROPYLAMINES AND THEIR OPTICAL STEREOISOMERS |
| 摘要 |
<p>Provided is an efficient method for the preparation of 3-aryloxy-3- arylpropylamines, their optical stereoisomers, and pharmaceutically acceptable salts thereof. The process allows for the isolation of 3-aryloxy-3- arylpropylamines in high yield and purity. The present invention further relates to a process for producing fluoxetine, tomoxetine, norfluoxetine, duloxetine, nisoxetine, and their optically enriched (R)- and (S)-enantiomers.</p> |
| 申请公布号 |
WO2007006132(A1) |
申请公布日期 |
2007.01.18 |
| 申请号 |
WO2006CA01051 |
申请日期 |
2006.06.27 |
| 申请人 |
APOTEX PHARMACHEM INC.;WANG, ZHI-XIAN;RAHEEM, MOHAMMED, ABDUL;WEERATUNGA, GAMINI;GUNTOORI, BHASKAR REDDY |
发明人 |
WANG, ZHI-XIAN;RAHEEM, MOHAMMED, ABDUL;WEERATUNGA, GAMINI;GUNTOORI, BHASKAR REDDY |
| 分类号 |
C07C217/54;C07C213/02;C07D333/20 |
主分类号 |
C07C217/54 |
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