摘要 |
The invention relates to fluorescent polymers soluble in an aqueous solution carrying at least 5 fluorophores which are distributed on a polymer and exhibit the following properties: fluorophores are water-soluble, the fluorophores are not self-associated in water at a concentration equal to or less than 10<SUP>-4</SUP> mol/l, preferably a concentration equal to or less than 10<SUP>-3</SUP> mol/l, the fluorophores which are free in the aqueous solution have a molar extinction coefficient greater than 1000 M<SUP>-1</SUP>?cm<SUP>-1</SUP>, , the fluorophores which are free in the aqueous solution have a quantum efficiency greater than 0.3, preferably greater than 0.6, said polymers have a fluorescence amplification factor equal to or greater than 0.35 per polymer Kg/mol, preferably greater than 0.45 per polymer Kg/mol. |
申请人 |
BIOMERIEUX S.A.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUTO SUPERIOR TECNICO;CHARREYRE, MARIE-THERESE;MANDRAND, BERNARD;MARTINHO, JOSE, MANUEL, GASPAR;RELOGIO, PAULA;SEQUEIRA FARINHA, JOSE, PAULO |
发明人 |
CHARREYRE, MARIE-THERESE;MANDRAND, BERNARD;MARTINHO, JOSE, MANUEL, GASPAR;RELOGIO, PAULA;SEQUEIRA FARINHA, JOSE, PAULO |