METHOD FOR PRODUCING 4(3H)-QUINAZOLINONE DERIVATIVE

摘要

Disclosed is a method for producing 2-methyl-3-{4- [3-(1- pyrrolidinyl)propoxy]phenyl}-5-trifluoromethyl-4(3H)-quinazolinone comprising a step for reacting 2-methyl-5-trifluoromethyl-4H-3,1-benzoxazine-4-one with 4- [3-(1-pirrolidinyl)propoxy]aniline or an acid addition salt thereof, or 4-(1- cyclobutyl-4-piperidinyl)oxyaniline or an acid addition salt thereof in the presence of an acetic acid catalyst.